张欣欣，副教授，博士研究生。
团队网站：http://biocc.hrbmu.edu.cn/xteam/index.html?member=zhangxinxin
E-mail：zhangxinxin@hrbmu.edu.cn
主要研究方向
癌症组学大数据研究
个人简介
长期致力于以肿瘤演化组学为核心的生物信息学研究，累计发表SCI论文28篇，其中，以第一作者或通讯作者身份在国际重要学术期刊《Nucleic Acids Research》（SCI IF：19.16，2篇）、《Briefings in bioinformatics》（SCI IF：13.994，1篇）、《Cancer research》（SCI IF：13.312，1篇）、《Neuro-oncology》（SCI IF：13.029，1篇）、《Genome Medicine》（SCI IF：12.3，1篇）、《Clinical Immunology》（SCI IF：10.19，1篇）等发表SCI论文12篇，累积影响因子202.069，研究成果CellMarker数据资源被评为2019年度中国生物信息学十大进展和十大数据库，所开发的生物医学大数据平台已累计被120多个国家超过46万次的访问。主持国家自然基金青年项目、中国博士后特别资助资助项目、中国博士后面上资助项目、黑龙江省博士后科学基金和哈尔滨医科大学创新课题项目4项，并作为核心骨干参与国家自然科学基金联合基金重点支持项目1项、面上项目3项、青年项目2项和省级教育规划课题1项。
发表SCI论文19篇，其中一作和通讯12篇：
1.Quan, F., X. Liang, M. Cheng, H. Yang, K. Liu, S. He, S. Sun, M. Deng, Y. He, W. Liu, S. Wang, S. Zhao, L. Deng, X. Hou,X. Zhang, Y. Xiao, Annotation of cell types (ACT): a convenient web server for cell type annotation. Genome Med, 2023. 15(1): p. 91.(SCI IF:12.3)
2.Zhang X,Lan Y, Xu J, Quan F, Zhao E, Deng C, Luo T, Xu L, Liao G, Yan M, Ping Y, Li F, Shi A, Bai J, Zhao T, Li X, Xiao Y. CellMarker: a manually curated resource of cell markers in human and mouse. Nucleic Acids Res. 2019;47(D1):D721-D8.(SCI: 19.16)
3.Zhang X, Quan F, Xu J, Xiao Y, Li X, Li Y. Combination of multiple tumor-infiltrating immune cells predicts clinical outcome in colon cancer. Clin Immunol. 2020;215:108412.(SCI: 10.19)
4.Wang Z, Xing K, Zhang B, Zhang Y, Chai T, Geng J,Qin, X,Zhang X, Xu C. Identification of Prognostic Gene Signatures by Developing a scRNA-Seq-Based Integration Approach to Predict Recurrence and Chemotherapy Benefit in Stage II-III Colorectal Cancer. Int J Mol Sci. 2022;23(20).(SCI: 6.208)
5.Lan Y, Liu W, Hou X, Wang S, Wang H, Deng M, Wang G, Ping Y,Zhang X.Revealing the functions of clonal driver gene mutations in patients based on evolutionary dependencies. Hum Mutat. 2022.(SCI: 4.7)
6.Zhang X, Xu J, Lan Y, Guo F, Xiao Y, Li Y, Li X.. Transcriptome analysis reveals a reprogramming energy metabolism-related signature to improve prognosis in colon cancer. PeerJ. 2020;8:e9458.(SCI: 3.061)
7.Zhang H, Luo S,Zhang X, Liao J, Quan F, Zhao E, Zhou C, Yu F, Yin W, Zhang Y, Xiao Y, Li X. SEECancer: a resource for somatic events in evolution of cancer genome. Nucleic Acids Res. 2018;46(D1):D1018-D26.(SCI: 19.16)
8.Xu L, Deng C, Pang B,Zhang X, Liu W, Liao G, Yuan H, Cheng P, Li F, Long Z, Yan M, Zhao T, Xiao Y, Li X. TIP: A Web Server for Resolving Tumor Immunophenotype Profiling. Cancer Res. 2018;78(23):6575-80.(SCI: 13.312)
9.Zhang H, Liao J,Zhang X, Zhao E, Liang X, Luo S, Shi J, Yu F, Xu J, Shen W, Li Y, Xiao Y, Li X. Sex difference of mutation clonality in diffuse glioma evolution. Neuro Oncol. 2019;21(2):201-13.(SCI: 13.029)
10.Zhang Y, Liao G, Bai J,Zhang X, Xu L, Deng C, Yan M, Xie A, Luo T, Long Z, Xiao Y, Li X. Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers. Mol Ther Nucleic Acids. 2019;17:362-73.(SCI: 10.183)
11.Xu J, Bai J,Zhang X, Lv Y, Gong Y, Liu L, Zhao H, Yu F, Ping Y, Zhang G, Lan Y, Xiao Y, Li X. A comprehensive overview of lncRNA annotation resources. Brief Bioinform. 2017;18(2):236-49.(SCI: 13.994)
12.Deng Y, Luo S,Zhang X, Zou C, Yuan H, Liao G, Xu L, Deng C, Lan Y, Zhao T, Gao X, Xiao Y, Li X. A pan-cancer atlas of cancer hallmark-associated candidate driver lncRNAs. Molecular oncology. 2018;12(11):1980-2005.(SCI: 7.449)
