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许艳

时间:2023-03-07 点击数:

   许艳,二级教授,博士研究生导师,民盟盟员。现任哈尔滨医科大学生物信息科学与技术学院生物医学工程教研室主任,黑龙江生物医学工程学会常务理事。

致力肿瘤生物信息学研究,主要专注于基于剂量效应的非编码RNA与转录因子对癌症协同调控的机制研究;整合多组学数据的癌症相关互作与协同调控紊乱机制的研究;基于单细胞测序数据的肿瘤耐药分子机制研究等工作。主持国家及省厅级课题9项。在《Briefings in Bioinformatics》,《Human Mutation》,《British Journal of Cancer》,《Epigenomics》,《Genomics》,《Journal of the Royal Society Interface》,等学术知名刊物上发表科研文章30余篇。获得计算机软件著作权1项,黑龙江省高校科技奖二等奖(第一)1项。

指导研究生科学研究,4人获国家级研究生奖学金,1人获省优秀研究生毕业生,4人获学校优秀研究生称号;指导本科学生毕业设计,5人获校优秀毕业生;指导大学生数学建模竞赛,获得国家级二等奖、省级二等奖、美国数学建模竞赛二等奖等奖项。

代表作SCI IF>5,JCR一区,第一通讯

  1. Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade,British Journal of Cancer.2022 Sep;127(5):916-926. SCI IF9.07

  2. Strongly preservedmodules between cancer tissue and cell line contribute to drug resistance analysis across multiple cancer types.Genomics. 2021Feb 26;113(3): 1026-1036.SCI IF5.734

  3. Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA Network. Frontiers in oncology.2021;10(3356).SCI IF6.244

  4. An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering, Aging (Albany NY). 2020 Jul 8;12(13):13172-13186.SCI IF5.682

  5. Identification and Characterization of the Copy Number Dosage-Sensitive Genes in Colorectal Cancer,MolecularTherapy-Methods & Clinical Development. 2020 Jun 24;18:501-510.SCI IF6.698

  6. Systematic identification of dysregulated lncRNAs associated with platinum-based chemotherapy response across 11 cancer types.Genomics, 2020,mar; 112(2):1214-1222.SCI IF5.734

  7. Optimization of cell lines as tumour models by integrating multi-omics data,Briefings in Bioinformatics,2017,18(3):515-529.SCI IF6.302

  8. An integrated approach to reveal miRNAs’ impacts on the functional consequence of copy number alterations in cancer,ScientificReports, 2015 Jun 23;5:11567.SCI IF5.228

  9. CNVD: Text Mining-based Copy Number Variation in Disease Database,Human Mutation,2012,33:11, E2375-2381.SCI IF5.761

    邮箱:xuyan@ems.hrbmu.edu.cn

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