许艳军(博士、副研究员,硕士生导师)。近年来,紧密围绕癌症非编码RNA调控及功能、肿瘤耐药及单细胞数据分析等进行研究并积累了丰富的工作基础。在《Briefings in Bioinformatics》、《Journal of Translational Medicine》、《Clinical Immunology》、《Comput Struct Biotechnol J.》、《DATABASE》、《Genes》等国际期刊上累计发表SCI论文30余篇;其中,第一作者(含并列)、通讯作者论文17篇,第一作者(第一位)单篇最高影响因子11.622。申请人主持国家自然科学基金项目1项,黑龙江省自然科学基金联合引导项目1项,哈尔滨医科大学青苗破土项目1项,获得2019年中华人民共和国教育部《高等学校科学研究优秀成果二等奖》1项。同时承担生物信息相关教学工作,主讲《药物基因组信息学》、《分子网络药理学》、《蛋白质组信息学》和《医用高等数学》等课程。作为第一指导教师指导学生获得东三省数学建模竞赛二等奖,大学生数学建模大赛美赛F奖等。
联系方式:xuyanjun@hrbmu.edu.cn
代表性研究成果:
Identification and comprehensive characterization of lncRNAs with copy number variations and their driving transcriptional perturbed subpathways reveal functional significance for cancer,Brief Bioinform. 2020 Dec 1;21(6):2153-2166. doi: 10.1093/bib/bbz113,第一作者,SCI影响因子:11.622
Identifying and characterizing drug sensitivity-related lncRNA-TF-gene regulatory triplets,Brief Bioinform. 2022 Sep;23(5): bbac366.通讯作者,SCI影响因子(2021): 13.994
Comprehensive analysis of ncRNA involvement in brain microglia immunology,Clinical Immunology.2022 Aug;241:109075.通讯作者,SCI影响因子(2021):10.19
Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data,Comput Struct Biotechnol J. 2022 Jan 22;20:838-849.第一作者,SCI影响因子(2021): 6.155
5. Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma,J Transl Med. 2022 Jun 21;20(1):277.通讯作者,SCI影响因子(2021): 8.44
6. Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data,J Transl Med. 2019 Aug 6;17(1):255. doi: 10.1186/s12967-019-2010-4,第一作者,SCI影响因子:4.124
Quantifying Risk Pathway Crosstalk Mediated by miRNA to Screen Precision drugs for Breast Cancer Patients,Genes (Basel). 2019 Aug 28;10(9):657. doi: 10.3390/genes10090657,通讯作者,SCI影响因子:3.759
RNAactDrug: a comprehensive database of RNAs associated with drug sensitivity from multi-omics data,Brief Bioinform. 2020 Dec 1;21(6):2167-2174. doi: 10.1093/bib/bbz142,并列一作,SCI影响因子:11.622
A comprehensive overview of oncogenic pathways in human cancer,Brief Bioinform. 2020 May 21;21(3):957-969. doi: 10.1093/bib/bbz046,并列一作,SCI影响因子:11.622
Dissecting immune cell stat regulation network reveals biomarkers to predict ICB therapy responders in melanoma,J Transl Med. 2021 Jul 8;19(1):296. doi: 10.1186/s12967-021-02962-8.,并列一作,SCI影响因子:5.53