许艳军

许艳军，副研究员，硕士生导师。近年来，紧密围绕癌症非编码RNA调控及功能、肿瘤耐药、单细胞及空间组学数据分析等进行研究并积累了丰富的工作基础。在《Nucleic Acids Research》《Briefings in Bioinformatics》、《Journal of Translational Medicine》、《Clinical Immunology》、《Comput Struct Biotechnol J.》、《DATABASE》等国际期刊上累计发表SCI论文30余篇；其中以第一作者/第一通讯作者身份发表论文单篇最高影响因子16.6。主持国家自然科学基金项目1项，黑龙江省自然科学基金联合引导项目1项，哈尔滨医科大学青苗破土项目1项，获得2019年中华人民共和国教育部《高等学校科学研究优秀成果二等奖》1项。同时承担生物信息相关教学工作，主讲《药物基因组信息学》、《分子网络药理学》、《蛋白质组信息学》和《医用高等数学》等课程。作为第一指导教师指导学生获得东三省数学建模竞赛二等奖，大学生数学建模大赛美赛F奖等。

主要研究方向：肿瘤多组学数据挖掘、深度学习、生物大数据平台开发

联系方式：xuyanjun@hrbmu.edu.cn

代表性研究成果（部分）：

1. Yanjun Xu^#, Yifang Zhang^#, Kaiyue Song^#, Jiaqi Liu^#, Rui Zhao, Xiaomeng Zhang, Liying Pei, Mengyue Li, Zhe Chen, Chunlong Zhang^*, Peng Wang^*and Feng Li^*.ScDrugAct: a comprehensive database to dissect tumor microenvironment cell heterogeneity contributing to drug action and resistance across human cancers.Nucleic Acids Research, 2025, 53 , D1536–D1546.第一作者，SCI影响因子:16.6

2. Feng Li^#, Xinyu Song^#, Wenli Fan^#, Liying Pei^#, Jiaqi Liu, Rui Zhao, Yifang Zhang, Mengyue Li, Kaiyue Song, Yu Sun, Chunlong Zhang^*, Yunpeng Zhang^* andYanjun Xu^*. SPathDB: a comprehensive database of spatial pathway activity atlas. Nucleic Acids Research, 2025, 53, D1205–D1214.通讯作者，SCI影响因子:16.6

3. Yanjun Xu^#, Tan Wu^#,Feng Li^#, Qun Dong^#, Jingwen Wang, Desi Shang, Yingqi Xu, Chunlong Zhang, Yiying Dou, Congxue Hu, Haixiu Yang, Xuan Zheng, Yunpeng Zhang*, Lihua Wang* and Xia Li*. Identification and comprehensive characterization of lncRNAs with copy number variations and their driving transcriptional perturbed subpathways reveal functional significance for cancer. Briefings in Bioinformatics, 2020 Dec 1;21(6):2153-2166.第一作者，SCI影响因子:11.622

4. Feng Li^#, Tan Wu^#,Yanjun Xu^#, Qun Dong^#, Jing Xiao, Yingqi Xu, Qian Li, Chunlong Zhang, Jianxia Gao, Liqiu Liu, Xiaoxu Hu, Jian Huang*, Xia Li* and Yunpeng Zhang*. A comprehensive overview of oncogenic pathways in human cancer. Briefings in Bioinformatics, 2020;21(3):957-969,共同第一作者，SCI影响因子:11.622

5. Qun Dong^#,Feng Li^#,Yanjun Xu^#, Jing Xiao^#, Yingqi Xu, Desi Shang, Chunlong Zhang, Haixiu Yang, Zihan Tian, Kai Mi, Xia Li* and Yunpeng Zhang*. RNAactDrug: a comprehensive database of RNAs associated with drug sensitivity from multi-omics data. Briefings in Bioinformatics. 2020 Dec 1;21(6):2167-2174.共同第一作者，SCI影响因子: 11.622

6. Congxue Hu#, Yingqi Xu#, Feng Li#, Wanqi Mi, He Yu, Xinran Wang, Xin Wen, Shuaijun Chen, Xia Li*,Yanjun Xu* and Yunpeng Zhang*. Identifying and characterizing drug sensitivity-related lncRNA-TF-gene regulatory triplets, Briefings in Bioinformatics，2022，通讯作者,SCI影响因子:9.5

7. Feng Li^#, Jingwen Wang^#, Mengyue Li^#, Xiaomeng Zhang, Yongjuan Tang, Xinyu Song, Yifang Zhang, Liying Pei, Jiaqi Liu, Chunlong Zhang , Xia Li*,Yanjun Xu* and Yunpeng Zhang*. Identifying cell type-specific transcription factor-mediated activity immune modules reveal implications for immunotherapy and molecular classification of pan-cancer. Briefings in Bioinformatics, 2024, 25(5), bbae368.通讯作者，SCI影响因子:6.8

8. Yanjun Xu^#, Jingwen Wang^#, Feng Li^#, Chunlong Zhang^#, Xuan Zheng, Yang Cao, Desi Shang, Congxue Hu, Yingqi Xu, Wanqi Mi, Xia Li^*, Yan Cao^*and Yunpeng Zhang^*, Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data,Computational and Structural Biotechnology Journal, 2022, 20:838-849,第一作者，SCI影响因子:6.0

9. Chunlong Zhang^#, Jiaxin Zhao^#, Wanqi Mi^#, Yuxi Zhang, Xiaoling Zhong, Guiyuan Tan, Feng Li, Xia Li*,Yanjun Xu* and Yunpeng Zhang*, Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma, Journal of Translational Medicine. 2022 Jun 21;20(1):277.通讯作者,SCI影响因子:7.4